Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VCP P55072 valosin containing protein 1.00 0.469 0.923
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TPPP O94811 tubulin polymerization promoting protein Cellular structure 0.20 0.570 0.692
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
TMED9 Q9BVK6 transmembrane p24 trafficking protein 9 Transporter 6.0E-03 0.666 0.538
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SARM1 Q6SZW1 sterile alpha and TIR motif containing 1 1.7E-10 0.682 0.346
RAN P62826 RAN, member RAS oncogene family Enzyme modulator 0.98 0.576 0.808
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769
PFN1 P07737 profilin 1 0.73 0.565 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
NEFM P07197 neurofilament medium 1.8E-02 0.674 0.577
NEFL P07196 neurofilament light 0.488 0.769